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REZUS-FAKTOR

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REZUS-FAKTOR (N-faktor), safedaest dar eritrositho (jismchahoi surkhi khun), ki khususiyathoi podzoi (antigeni) dorad. Rezus-faktorro olimoni avstriyagi K. Landshteyner va A. Viner soli 1940 dar eritrosithoi Masasiz geziz yoftand (nomash niz az hamin jost). Yakchand antigonhoi gunoguni sistemai Rezus-faktor mavjudand, az jumla guruhi Ng ki bo N sistemai umumii N — Ng-ro tashkil me-dihad. In sistema 3 namudi harkhelai N-agglyutinogen (B, S, E) va 3 namudi harkhelai Ng-agglyutinogeya (s, (1, e)-ro darbar megirad. Rezus-faktor, chun alomati dominanti az nasl ba nasl meguzarad va dar davomi hayot tagyir nameyobad. Rezus-faktor dar khuni taqriban 85% odamon vujud dorad (shakhsoni N-ashon musbat), vale 15^—18% oda-mon Rezus-faktor nadorand (N-ashon manfi). Miqdori shakhsoni N-ashon manfi ba sharoiti geografi vobasta ast, ki in khel kason dar Garb beshtar va dar Sharq kamtar yoft meshavand.

Odamoni N-ashon manfi yagon khel alomati kasali nadorand va ba haddi kofi solimand. Ba etibor giriftani Rezus-faktor hangomi khunguzaroni hatmist, zero in amal baroi shakhsoni N-ashon manfi khatar dorad. Nabudani Rezus-faktor dar zanho, makhsusan dar davri homiladori khavfnok ast, chunki dar bayni modari N-ashon manfi va janini N-ash musbat hodisai Rezus — mukholifati masuni (immuniteti) ruy medihad. Dar natijai in kudak dar batni modar halok va isqot meshavad; agar kudak namurda tavallud shavad, u ba kasalii khunobshavy (hemoliashavi) duchor megardad, yo tamomi badanash obvaram mekunad. Dar mavridi Rezus — mukholifat beshtar istikhroji janin, bachapartoi, chalazoi ruy medihad.

P e sh g i r i: dar vaqti Rezus — mukholifat asosan nagirondani (abort nakunondan) hamli nakhustin; hangomi khunguzaroni boshad, intikhob namudani khuni az jihatya guruh  va rezus munosib va ba badan guzaronidani gamma-globulini ziddi rezus.

Adabiyot: Solovyova T. G., Rezus-faktor i ego znachenie v klinicheskoy praktike, Leningrad, 1963; Persianinov L. S., Nesovmestimost krovi materi i ploda—dar kitoi: «Akusherskiy seminar», tom 2, Tashkent, 1973. S. H. Hakimova.

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