Parkinsonizm

Parkinsonizm, b e m o r i i  Parkinson, bemorii muamini sistemai asabi markaziro guyand, ki boisi illati funksiyai uzvhoi kharakat megardad. Parkinsonizmro bori avval  dukhturi anglis J. Parkinson (1817) bayon kardaast. Ba in bemori beshtar odamoni miyonasol giriftor meshavand. Sababi asosii ba vujud omadani Pankirsonizm ensefalit (illati magzi sar) aterosklerozi ragkhoi mayna, oseb  yoftaii cap, zahroludshavi va gayra me­boshad.

Hangomi Parkinsonizm muvozinati bayni mediatorhoi (moddakhoe, ki barangezishro az yak hujayrai asab ba khujayrai digar va az asab ba uzvhoi kori meguzaronand) mayna vayron meshavad. Chunin holat dar natijai norasoii mubodilai katekholamilho, ; masalan, dofamin dar qismi zeriqishrii mayna ba vujud meoyad. Dar vaqti Parkinsonizm dastu poy beist melarzad, az dahon ob meravad, harakat sustu kas  karakht meshavad.

M u o l i j a: istemoli doruhoi kholinolitie. ki ba sistemai asabi markazi tasir mekunand va preparati I-dofa, ki konsentrasiyai dofaminro mutadil megardonad, inchunin jarrohi.